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Folate

L-5-Methyltetrahydrofolate and Calcium Folinate (Vitamin B9)

Nutrient Form:
Vitamin
Found In:
Beef Liver, Leafy Green Vegetables & Grains
Bioavailability:
The methylated form of folate (vitamin B9) has been shown to have unique properties allowing it to access the right parts of your body faster and more accurately than other forms, resulting in optimized absorption rates.

Description

Folate (Vitamin B9) works with certain methyl groups to synthesize neurotransmitters and hormones related to mood. Similar to Vitamin B6 and Vitamin B12, Folate is depleted or exists at low levels when certain antidepressants are taken.
Balances Biochemistry
Folate (Vitamin B9) works with certain methyl groups to synthesize neurotransmitters and hormones related to mood and cognition, such as dopamine, serotonin, and norepinephrine. As a key building block to this process, we’ve included it in our Restore formula to promote healthy, sustainable neurotransmitter production.
Key Nutrient Repletion
Similar to Vitamin B6 and Vitamin B12, Folate (Vitamin B9) is found to be depleted or at low levels when certain antidepressants are taken. We included it in our formula to help restore these nutrients to normal levels in your body.

Ingredients Backed By Science

We review extensive clinical research, so you can feel confident about what you’re putting into your body. We’ve included a few key studies below, so you can evaluate the clinical results too.

Tabriz University of Medical Sciences

Nutritional Status in Patients with Major Depressive Disorders

Results indicate that supplementing with Folate and Vitamin B12 can help address key nutritional factors contributing to mood and cognitive disorders.
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MRC Neuropsychiatric Research Laboratory

Treatment of Depression: Time to Consider Folic Acid and Vitamin B12

Found a correlation between B-Vitamin deficiencies with mood and cognition, as well as decreasing levels of certain molecules that have been linked to mood-related disorders.
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Kuopio University Hospital

High Vitamin B12 Level and Good Treatment Outcome May be Associated in Major Depressive Disorder

Results showed that Folate supplementation improved overall mood levels in individuals.
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Australian National University

Oral Folic Acid and Vitamin B12 Supplementation to Prevent Cognitive Decline in Community-Dwelling Older Adults with Depressive Symptoms

Vitamin B12 and Folic Acid in long-term settings saw improvement in cognitive function, including the reduction in psychological stress.
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USDA; Tufts University

Depression and Folate Status in the US Population

A U.S. population study found that low folate status was detectable in depressed members of the general population. Folate is a key vitamin in the neurotransmitter production process and deficiencies can manifest in mood swings and decreased cognitive function.
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