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SAMe

S-Adenosyl Methionine

Nutrient Form:
Amino Acid
Found In:
Poultry, Beef, Fish & Pork
Bioavailability:
Although there are more bioavailable forms of SAMe on the market, they are currently difficult to source. However, this version remains highly effective in its current dosage found in our Restore formula.

Description

SAMe is a unique combination of ATP (the primary carrier of chemical energy in our body) and the amino acid methionine. Together, they create a powerful methyl system that plays a key part in the production of neurotransmitters, including dopamine, serotonin, and norepinephrine. SAMe works together with Vitamin B12, Folate, and Riboflavin to make sure your neurotransmitter production is regulated at a healthy, sustainable level.
Balances Biochemistry
Working together with B-Vitamins in our Restore formula, SAMe is an important component to the production of key neurotransmitters related to mood regulation. Healthy neurotransmitter production is critical to maintain mood and cognition in your body's neurosystem.
Key Nutrient Repletion
Similar to Vitamin B12 and Folate, SAMe has been found in low circulating amounts when antidepressant medications are taken over an extended period of time. We included it to ensure you are receiving a dose of this important nutrient to aid healthy, sustainable neurotransmitter production.

Ingredients Backed By Science

We review extensive clinical research, so you can feel confident about what you’re putting into your body. We’ve included a few key studies below, so you can evaluate the clinical results too.

University of Massachusetts - Lowell; Framingham State University; Advanced Memory Dynamics; Worcester State University; Loyola University Maryland; University of Maryland

A Phase II Randomized Clinical Trial of a Nutritional Formulation for Cognition and Mood in Alzheimer's Disease

Found that a blended nutraceutical combination of SAMe, B-Vitamins, and Vitamin E helps to regulate and improve mood.
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Università La Sapienza; Viale dell'Università

A Double-blind, Randomized Parallel-group, Efficacy and Safety Study of Intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) Versus Imipramine in Patients with Major Depressive Disorder

SAMe's plays a critical role in the production of key mood-related neurotransmitters, helping to regulate the body's natural production cycle.
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Clinica delle Malattie Nervose e Mentali dell'Università di Roma

Effect of S-Adenosyl-L-Methionine (SAMe) Upon Depressive Symptoms

SAMe showed an ability to positively impact mood and cognition.
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Florida International University; Yunnan University

Insights Into S-adenosyl-l-methionine (SAMe)-dependent Methyltransferase Related Diseases and Genetic Polymorphisms

Outlines the unique flexibility of SAMe and it's critical role in the production of key mood and cognitive-related neurotransmitters.
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